By Hanns-Christian Gunga, Victoria Weller von Ahlefeld, Hans-Joachim Appell Coriolano, Andreas Werner, Uwe Hoffmann
This publication comprehensively describes the physiological adjustments and outcomes that happen in people in the course of spaceflight. It in particular offers the variations of the cardiovascular and the breathing approach. particular alterations taking place after 10, 20 or extra days in house are depicted. moreover, the booklet explains a number of potent countermeasures which are required upon go back of the astronauts to Earth.
The ebook is a must have for all biomedical and medical researchers within the box of cardiovascular biology and breathing, and a desirable examining for all laymen, who desire to comprehend a section extra approximately spaceflight study and technology.
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Additional info for Cardiovascular System, Red Blood Cells, and Oxygen Transport in Microgravity
Ertl et al. measured a decrease in stroke volume, which is in line with a decreased blood volume and will induce a lower cardiac output provided that the heart rate remains unchanged . Measurements of 26 cosmonauts onboard the Salyut-7 and Mir stations displayed person-specific trends of cardiac output (CO) and stroke volume (SV) in the first 3 months of flight. Thereafter, however, the cosmonauts displayed a unison trend of decreasing SV and CO during 4–6 flight months . Hypovolemia induced by space flight leads to an under-filling of the heart chambers, which decreased the SV and thereby the CO.
This triggers the stretch receptors sending the baroreflex into action. It was first believed that a reduction in blood volume is achieved by increased diuresis as part of a feedback mechanism. This mechanism was first described by the gravitational physiologists Gauer and Henry and is therefore termed the Gauer– Henry Reflex . Thoracic stretch receptors suppress the production of the Antidiuretic Hormone (ADH). This means that less water is reabsorbed in the kidneys and more urine is produced.
Aubert AE, Beckers F, Verheyden B (2005) Cardiovascular function and basics of physiology in microgravity. Acta Cardiol 60(2):129–151 62. Moore D, Bie P, Oser H (1996) Biological and medical research in space: an overview of life sciences research in microgravity. Springer, Berlin 63. Bungo MW, Goldwater DJ, Popp RL, Sandler H (1987) Echocardiographic evaluation of space shuttle crewmembers. J Appl Physiol 62(1):278–283 64. Frey MA (1996) Space research activities during missions of the past. Med Sci Sports Exerc 28 (10 Suppl):S3–S8 65.
Cardiovascular System, Red Blood Cells, and Oxygen Transport in Microgravity by Hanns-Christian Gunga, Victoria Weller von Ahlefeld, Hans-Joachim Appell Coriolano, Andreas Werner, Uwe Hoffmann