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The mean age of patients in both groups was 37 years, and 70 percent of the patients were female. 1). Patients with chronic fatigue syndrome indicated a greater degree of functional impairment and were more likely to be currently employed. Using the entire life as time frame, mood disorders were diagnosed in 45 patients (75 percent) with chronic fatigue syndrome and 46 fatigue control subjects (77 percent). Major depression with recurrent episodes was the most common psychiatric disorder in this cohort, being identified in 26 of the chronic fatigue syndrome patients (43 percent) and 32 members of the control group (53 percent).

002). The authors pointed out that the prevalence of symptoms considered specific for chronic fatigue syndrome, such as postexercise myalgia, was similar in chronic fatigue syndrome and major depression groups (83 versus 67 percent). Most patients with chronic fatigue syndrome attributed their symptoms to a physical cause. , 1991). The authors identified somatization disorder in 28 percent of 60 patients with chronic fatigue syndrome, but in only 5 percent of a gender- and age-matched control group with a chief complaint of tiredness and without symptomatic evidence of chronic fatigue syndrome.

01). As expected, these variables were also strong predictors for the presence of current psychiatric morbidity. The previous use of psychotropic medications showed a significant correlation with the severity of psychological distress. Somatic symptoms were significantly more prevalent among patients with chronic fatigue syndrome. The observation retained its validity for symptoms not part of the syndrome’s definition. For instance, compared with subjects without fatigue, patients with chronic fatigue syndrome were more likely to endorse nausea (69 versus 21 percent), stomach pain (50 versus 25 percent), palpitations (44 versus 15 percent), frequency of urination (44 versus 12 percent), eye pain (42 versus 13 percent), shortness of breath (33 versus 4 percent), and tremor (25 versus 12 versus 6 percent [chronic fatigue syndrome, idiopathic fatigue, and control group, respectively]).

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